Canine Mat Test Leptospirosis

1 2 if leptospirosis is suspected and the initial titer is not confirmatory a convalescent titer should be performed.

Canine mat test leptospirosis.

19 20 a single acute serum sample is not as sensitive 50 while. Pcr performed on blood and or urine can be a valuable tool to aid in diagnosis of leptospirosis. Microscopic agglutination test the mat is the gold standard when testing for leptospirosis. 2 4 for this test the patient s serum is sent to a referral laboratory where it is combined with live leptospires.

The snap lepto test enhances your protocol allowing you to test for antibodies to leptospirosis during the patient visit and start treatment immediately. Canine leptospirosis is a potentially deadly disease so timely treatment is essential. However the application of a polymerase chain reaction pcr assay can provide earlier confirmation of suspected cases. A second serologic test is available the.

Canine leptospirosis is definitely diagnosed by demonstrating seroconversion in paired serum samples from the acute and convalescent period by the microagglutination test mat. Diagnostic tests for dogs suspected of having leptospirosis include antibody based tests and polymerase chain reaction pcr. Leptospirosis is the microscopic agglutination test mat 2 4 17 to perform this test dilutions of the patient s serum are added to suspensions of live leptospi ral serovars. Even in face of such limitations active leptospiral infection was determined in four dogs exclusively by mat while pcr was able to detect 10 infected dogs at clinical presentation that a single mat sample evaluation could not reinforcing that the use of multiple tests is beneficial for improving the diagnosis of canine leptospirosis in practical situations in which the clinical outcome and.

18 a 4 fold increase in titer indicates seroconversion and a diagnosis of leptospirosis. It is caused by infection with antigenically distinct serovars of the spirochete leptospira interrogans sensu lato. Paired acute and convalescent microscopic agglutination test mat are diagnostic for leptospirosis. The most common diagnostic test used today to aid in the diagnosis of canine leptospirosis is the mat which detects antibodies capable of agglutinating cultured organisms 5 due to the complexity in per forming the mat this test is only performed in commercial diagnostic laboratories.

Leptospirosis is a zoonotic disease of worldwide veterinary significance in many animal species. These serovars can be further divided into pathogenic non pathogenic and opportunistic. Currently over 250 different leptospiral serovars are known worldwide. In a patient with consistent clinical signs and clinicopathological abnormalities a single mat titer of 1 800 or greater is often considered to be diagnostic for leptospirosis.

How is the mat used in the diagnosis of canine leptospirosis. The mat tests for leptospira specific antibodies whereas the other tests demonstrate the presence of the organism itself.